Needlefree Catheter Patency Device

Innovative technology that reduces reflux to help maintain catheter patency while providing a safe and effective microbial barrier.

  • Minimize delay in therapy and procedures.
  • Minimize unnecessary patient discomfort.
  • Reduce length of stay.
  • Decrease the need for and risks of declotting agents.
  • Reduce the risk of releasing a blood clot into the bloodstream.



The Neutron Catheter Patency Device Reduces Reflux to Help You Minimize Occlusions

Maintaining catheter patency and minimizing occlusions can be important steps in your efforts to enhance patient safety, improve patient outcomes, and reduce costs.

But despite your efforts, central line occlusions, which are frequently caused by blood reflux,1 remain a significant issue that can result in delays in critical patient care, increased risk of infection, and increased healthcare costs. That's why reducing the risk of catheter occlusions may help you decrease the need for expensive declotting agents such as t-PA, and reduce the clinical costs associated with managing catheter occlusions.

Neutron's breakthrough anti-reflux technology helps you stop occlusions before they start, while providing a safe and effective microbial barrier.

Unlike other technologies, such as positive displacement needlefree connectors, Neutron is the only device FDA-cleared to prevent multiple forms of reflux into a catheter and utilize ICU Medical’s patented needlefree connector technology which has been proven to minimize contamination and help you lower the risk of catheter related bloodstream infections (CRBSI)2,3,4


Neutron May Help You Reduce Catheter Occlusions by

  • Avoid Delays in Critical Patient Care

    Neutron may help avoid delays in therapy of critical intravenous medications (e.g., antibiotics and oncolytics), nutritional support, and blood products.
  • Avoid Patient Discomfort and Pain

    Neutron may help avoid patient discomfort and pain caused by unnecessary needlesticks, catheter restarts, and manipulating the IV site.
  • Avoid Unnecessary Costs

    Neutron may help minimize unnecessary costs that add up when treating an occlusion.
  • Help Reduce Risk of Infection

    Neutron may help reduce the risk of infection by preventing thrombosis and minimizing IV line manipulation.

Designed to Prevent Multiple Causes of Reflux into a Catheter

Reflux of blood into the catheter has been shown to contribute to biofilm formation and catheter occlusion.

How it Works

Superior Anti-Reflux Technology

Because of an innovative design that incorporates a patented bi-directional silicone valve and bellows feature to help prevent reflux, Neutron helps maintain catheter patency during times when traditional connectors have been shown to occlude most often.

Add a Splash of Color for Quick and Easy Line Identification.

Customize Neutron with a variety of color-coded rings to help you improve IV line management and avoid medication mix-ups.

Residual Volume: 0.1 mL
Flow Rate at Gravity: 100 mL / minute
Blood Compatibility: Yes
MRI Compatibility: Yes
High Pressure Compatibility: 10 mL / second
Alcohol: Yes
Lipids: Yes
Chlorhexidine: Yes
Chemotherapy: Yes
Neutron's saline flush option allows you to reduce risks, cost, and time associated with Heparin use.


  1. Gorski, Lisa A MS, RN, CS, CRNI. Central Venous Access Device Occlusions: Part 1: Thrombotic Causes and Treatment. Home Healthcare Nurse. 21:2 115-121, February 2003.
  2. Ryder M, James G, Pulchini E, Bickle L, Parker A. Differences in bacterial transfer and fluid path colonization through needlefree connector-catheter systems in vitro. Presented at the Infusion Nursing Society Meeting, May 2011.
  3. Moore C, RN, MBA, CIC. Maintained Low Rate of Catheter-Related Bloodstream Infections (CR-BSIs) After Discontinuation of a Luer Access Device (LAD) at an Academic Medical Center. Poster presented at the annual Association for Professionals in Infection Control and Epidemiology (APIC) Conference 2010, Abstract 4-028.
  4. Evaluation of the Clave® technology and resistance to microbial ingress. Report of a study commissioned by ICU and conducted by Nelson Laboratories, 2008. M1-1212 rev. 03.
  5. ICU Medical Study Summary. Observational In-Vivo Evaluation of the Neutron™ Needlefree Catheter Patency Device and its Effects on Catheter Occlusions in a Home Care Setting, 2011.
  6. Yebenes J, Delgado M, Sauca G, Serra-Prat M, Solsona M, Almirall J, et al. Efficacy of three different valve systems of needlefree closed connectors in avoiding access of microorganisms to endovascular catheters after incorrect handling. Crit Care Med 2008;36: 2558–2561.
  7. JD Brown, HA Moss, TSJ Elliott. The potential for catheter microbial contamination from a needleless connector. J Hosp Infect. 1997.; 36:181-189.
  8. Ryder M, RN, PhD. Bacterial transfer through needlefree connectors: Comparison of nine different devices. Poster presented at the Annual Society for Healthcare Epidemiology of America (SHEA) conference 2007.
  9. Guideline for the Prevention of Intravascular Catheter-Related Bloodstream Infections, Final Issue Review, May 17, 2010.
  10. Data on file at ICU Medical. Low Volume Flush Characteristics of Unique Needlefree Connectors M1-1223 Rev. 1.

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