The Challenge
Balancing oxygen delivery with oxygen demand is an
important part of early goal-directed therapy (EGDT) for
identification and treatment of septic shock.
Sepsis is a
dangerous medical condition characterized by widespread tissue
inflamation resulting from the body's immune response to infection.
If left untreated, sepsis can progress to a more severe state,
identified by hypoperfusion and organ failure. This condition can
worsen when a patient becomes hypotensive, and ultimately lead to
septic shock (within 24 hours).1 Combined, these conditions
have a mortality rate greater than 30%.2 Because the disease progresses
so rapidly, early diagnosis is essential. EGDT attempts to restore
the balance between the body's oxygen supply and demand. This
requires clinicians to assess healthy tissue oxygenation by
measuring venous oxygen saturation.1
Our Solution
The
TriOx™ SvO2 PA Catheter and
TriOx ScvO2 Central Venous Catheter and Probe
were developed in order to help clinicians optimize oxygen supply
and demand and initiate EGDT in cases of severe sepsis or septic
shock.
The TriOx 3-wavelength oximetry technology provides unparalleled
accuracy, as it filters artifact caused by cell orientation, vessel
wall reflections, and changes in pH. This technology is also
offered in the form of a central venous catheter (CVC) probe, which
converts most CVCs into ScvO2 monitoring catheters,
allowing clinicians to scale monitoring capability to meet
therapeutic goals without replacing an existing CVC. The accuracy
of TriOx oximetry technology can be essential in the initiation of
EGDT.
- Emmanuel Rivers, et al. Early and innovative interventions for
severe sepsis and septic shock: taking advantage of a window of
opportunity, CMAJ, October 25, 2005, 173(9)
- Angus, DC, Linde-Zwirble WT, Lidicker J, et. al. Epidemiology
of severe sepsis in the United States: analysis of incidence,
outcome, and associated costs of care. Crit Care Med
2001;29:1303-10
